Effects of Vitamin E on Chronic Haematoxicity of Paraquat Exposed Male Albino Rats (Rattus norvegicus)
نویسندگان
چکیده
Paraquat is an environmental pollutant that associated with some disorders including alteration of harmatological indices and a concern to public health. Vitamin E has antioxidant property other characteristic roles ameliorate toxic effect. 200 male albino rats weighing 0.2±0.02kg on the average were divided into four main groups (A, B, C, D) 50 in one group. The “A” group was not served paraquat solution used as control Group “B”, “C”, “D” being treatment given dose rates 0.02g, 0.04g, 0.06g, per kg rat respectively every two weeks for three months. further had subgroups. “A”, “A0” “AVE”; “B0” “BVE”; “C” “C0” “CVE”; “D”, “D0” “DVE” subgroups “A0”, “B0”, while “AVE”, “BVE”, “CVE” fed orally 500mg vitamin therapy week. Treatment began months after treatment. At end weekly month, sacrificed their blood samples obtained analyzed PCV, Hb, WBC, neutrophil lymphocyte. A0, B0, C0 D0 intergroup comparison statistically significant, p-value<0.05 PCV Hb levels lymphocyte no statistical significance. Ave, Be, Cve Dve neutrophils significance among groups. Intra showed only significant between groups, p-value<0.05. This study confirms potent treating toxicity month
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ژورنال
عنوان ژورنال: Archives of current research international
سال: 2022
ISSN: ['2454-7077']
DOI: https://doi.org/10.9734/acri/2022/v22i330280